There are known to be 740 bird species in Mozambique, including 20 globally threatened species and two introduced species, and over 200 mammal species endemic to Mozambique, including the critically endangered Selous’ zebra, Vincent’s bush squirrel and 13 other endangered or vulnerable species.

At 309,475 sq mi (801,537 km2), Mozambique is the world’s 36th-largest country. It is comparable in size to Turkey. Mozambique is located on the southeast coast of Africa. It is bound by Eswatini to the south, South Africa to the southwest, Zimbabwe to the west, Zambia and Malawi to the northwest, Tanzania to the north and the Indian Ocean to the east. The country is divided into two topographical regions by the Zambezi River. To the north of the Zambezi River, the narrow coastal strip gives way to inland hills and low plateaus. Rugged highlands are further west; they include the Niassa highlands, Namuli or Shire highlands, Angonia highlands, Tete highlands and the Makonde plateau, covered with miombo woodlands. To the south of the Zambezi River, the lowlands are broader with the Mashonaland plateau and Lebombo Mountains located in the deep south. The country is drained by five principal rivers and several smaller ones with the largest and most important the Zambezi.

Protected areas of Mozambique include thirteen forest reserves, seven national parks, six nature reserves, three frontier conservation areas and three wildlife or game reserves. The country had a 2019 Forest Landscape Integrity Index mean score of 6.93/10, ranking it 62nd globally out of 172 countries.